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Update: Took her to the vet yesterday afternoon and they confirmed that she is having an allergic reaction to flea saliva.  They put more flea stuff on her (Advantage which he said was stronger and better than what I had been using - Bob Martin), and some steroid tablets to stop the itching. ...

EDIT: She originally had a little bit of bright red blood and mucus in her poo (I assume it was her and not her sister who has been behaving normally) which was a mixture of soft/normal. As soon as I noticed this I treated them both for worms and have not noticed any more blood.

I have two female cats, sisters, around 1.5years old.  In the last couple of weeks, one has started isolating herself, staying downstairs all the time.  I thought she may have worms so gave her worm tablets in her food and have treated her with flea treatment as she has scabs on her from where...