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Thanks everyone!  Wasn't trying to be rude.  I will contact the vet. 

She has her own room that the dog isn't allowed in and honestly he avoids her as much as he can. Just so everyone knows.....I've had cats before.  I've been around animals all my life.  Cows, chickens, dogs, cats, horses, pigs,  lizards, snakes,fish....It's not like I'm not an animal person...

I've had her since she was 6 weeks old........and never a bad experience.

Her litter box is now in the laundry room (for months now).  She has been fine for months and all the sudden started again.

I use to have her litter box in the bathroom and she would pee right next to it.  Yes, it was clean!  :-)

Thanks for your comment.  You can pet her (this is even when we lived alone together) and all of the sudden she didn't want to be petted anymore will hiss and spit.  As for being a stress head, I would agree.  I've tried the diffuser spray and it did not work.  I did try some liquid that you put...

I'm still going to disagree.  My cat has done this from time to time (yrs before the dog and trust me the dog is scared of her).  She is not threaten in anyway.  She hisses when you try and pet her and yet will rub up against you all within a matter of seconds.  She goes to the vet and there are...

Sorry people but my cat gets mad and does pee in my bathroom!  She goes to the vet and is fine for months and than she gets irritated about something and is upset.  We have had a dog for several months now (she did this long before he came around) and now all of the sudden she has started again...