Once a queen goes into heat or estrus, she may stay in heat for several days, to 2-3 weeks. Some queens, once they are sexually mature and enter estrus, do not come out of heat unless and until they are either bred to a full male cat, or spayed. The majority of queens will cycle in and out of...
The best thing you can do for these kittens is to spay and neuter each one before placing into a new home. Having an adoption contract makes no difference at all once they are out of your house - it's out of your control. Many people will have their cat declawed at the same time as S/N because...