I recently got collars for Slasher and Ripper. They're fleece, ordered from http://softfleecepetproducts.com/.

I assume that I should remove the collar when applying a flea medication such as Frontline Plus?

Should the collar be kept off overnight while the medication dries and spreads?

I take the collars off and leave them off overnight.

I always took Mittens' collar off of her when i put Frontline on. Monster too. But they both keep losing their collars. Anyway, i always left them off until the Frontline was dry the next day.

Thanks :)

Probably a good idea to leave the collars off for a few hours. My cats don't wear collars, so it wouldn't be a problem for me :)